Andrei Irimia

Assistant Professor of Gerontology and Neuroscience
Ethel Percy Andrus Gerontology Center
USC Leonard Davis School of Gerontology

Andrei   Irimia

Research Topics

  • traumatic brain injury in older adults
  • brain aging
  • connectomics
  • cerebral plasticity prompted by traumatic brain injury
  • neuroimaging
  • blood-brain barrier
  • cerebral microhemorrhage
  • aging in atypical populations

Research Images

3D model of a human brain affected by traumatic brain injury (TBI). The cerebrum is translucent whilst the ventricles are blue. Areas affected by hemorrhage are drawn in red; they are surrounded by edematous areas (green). These models generated using multimodal neuroimaging allow one to quantify neuroanatomic pathology and to relate it to clinical outcome and deficits. Automatic parcellation of the cerebral cortex obtained from magnetic resonance imaging subsequent to tissue classification. The surface of each lobe is drawn using a different color scheme, and a different color is used for each gyrus and sulcus. Connectogram of the healthy aging brain. The connectogram is a graphical representation of the human connectome and has been pioneered by our laboratory. This visualization has been adopted by neuroscience research groups around the world and has won a prestigious award for best visualization. High-resolution finite element models (FEMs) of the brain affected by traumatic brain injury. These sophisticated models allow us to localize the electrical activity of the brain using electro- and magneto-encephalography (EEG and MEG), and thereby infer important information on the physiological changes prompted by brain injury.

Research Overview

My research involves the use of multimodal neuroimaging (MRI, MRA, PET, CT, EEG, MEG) to understand how traumatic brain injury (TBI) alters brain aging. Specific interests include (1) TBI in older adults; (2) aging- and TBI-related reorganization of the human connectome; (3) the relationship between TBI and Alzheimer's disease; (4) consequences of aging and TBI upon neural function, cognition and affect (major depressive disorder); (5) cardiovascular disease effects upon brain aging in atypical populations (the Tsimane people of Bolivia).

Contact Information

Mailing Address Ethel Percy Andrus Gerontology Center
USC Leonard Davis School of Gerontology
Office Location Room B14
Office Phone (213) 821-5997
Lab Location GERO B14
Lab Phone (213) 821-5997
Fax (213) 740-5150
Office Location Room B14



  • PhD, biophysics, Vanderbilt University

Selected Publications

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