USC researchers awarded NIH grant to build a new model of hippocampal neurodegeneration in Alzheimer’s disease

With a new model of the brain region essential to memory formation, from cells to whole-brain networks, a team led by NGP Faculty Michael Bienkowski hopes to identify critical changes in the progression of Alzheimer’s disease that could point the way to earlier, more effective treatments.

Hippocampal pyramidal neurons are critical for learning and memory. Degeneration of hippocampal neurons and their circuit connections is a key driver of cognitive decline in Alzheimer’s disease. Photo/ Stevens INI

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