Molecular Biology and Genetics

Don Arnold

  • Cellular Neurobiology
  • Membranes & Transport

Berenice A. Benayoun

  • How is remodeling of chromatin landscapes during aging and in response to longevity interventions determined and regulated?
  • How are specific aspects of transcriptions regulated and impaired during aging?
  • What role does sex, an important yet understudied factor in aging and longevity, play in the regulation of aging?

Karen T Chang

  • Drosophila models for Down syndrome and Alzheimer’s disease
  • Mechanisms regulating synaptic vesicle endocytosis
  • Mechanisms underlying synaptic plasticity
  • Mechanisms of mitochondrial trafficking
  • Mitochondrial dynamics in neurological disorders

Dion Kai Dickman

  • Synapse development, function, and plasticity in Drosophila

Ksenia Gnedeva

  • Sensory organ development and disease
  • Hearing & Balance
  • Retina
  • Cellular and molecular basis of regeneration
  • Gene therapy

Bruce E. Herring

  • Synaptic function
  • Synaptic plasticity
  • Neuropsychiatric and Neurodevelopmental Disorders

Michael W. Jakowec

  • Animal models of Parkinson’s disease.
  • Molecular mechanisms of exercise-induced neuroplasticity in the basal ganglia.
  • Interactions between dopamine and glutamate within the basal ganglia and their role in contol of motor behavior.
  • Development of new therapeutic modalities for Parkinson’s disease.

Chien-Ping Ko

  • Synaptic structure, function, formation, repair, and maintenance.
  • Synapse-glia interactions at the neuromuscular junction.
  • Cellular and molecular mechanisms of the pathogenesis of Spinal Muscular Atrophy (SMA).

Pat Levitt

  • Development of Neuronal Diversity, Neural Circuitry and Synapses in Neocortical and Brainstem Autonomic Networks
  • Neurodevelopmental Mechanisms of Social-Emotional Behavior
  • Gene regulatory networks
  • Clinical studies of children with ASD and medical co-morbidities
  • Impact of early adverse experience on brain development and behavior
  • Translating neuroscience of early brain and child development for public policy changes

Emily R. Liman

  • Ion channel biophysics
  • Sensory biology
  • Pain and taste transduction

Valter D. Longo

  • Aging
  • Cellular Neurobiology
  • Microbial/Invertebrate Genetics
  • Cancer

David McKemy

Aaron Nagiel

  • Synaptogenesis
  • Neural circuit formation
  • Retinal development
  • 3-dimensional retinal organoids
  • Inherited retinal diseases

Christian J. Pike

  • Regulation of Alzheimer’s disease pathogenesis
  • The role of sex steroid hormones in Alzheimer’s disease
  • Relationships between obesity, type 2 diabetes, and Alzheimer’s disease
  • Signaling pathways regulating neuronal apoptosis and neuroprotection

Huizhong W. Tao

  • Cellular neurobiology
  • Developmental neurobiology
  • Sensory neurobiology
  • Central visual processing

Li I Zhang

  • Synaptic circuitry mechanisms for sensory information processing
  • Technical innovations for tracing brain circuits
  • Neural circuits for innate behavior
  • Synaptic and cellular basis for development and plasticity of neural circuitry
  • Neural circuitry basis for sensory processing disorders

Zhen Zhao

  • Alzheimer’s disease and related dementia
  • Blood brain barrier and vascular-neuronal interaction
  • The role of innate immunity in CNS diseases and injuries

Berislav V. Zlokovic, MD, PhD

  • Ischemia and Stroke
  • Activated Protein C System
  • Amytrophic lateral sclerosis
  • Blood-Brain Barrier
  • Cerebral microcirculation and regulation of cerebral blood flow