Wang, Lu

Our lab aims to push the boundary of our understanding of human brain in development and related disorders with discoveries focused on non-neuronal cells, environmental stress, and genetic mutations, leveraging the stem cell-based organoid/PCCO-assembled model in combination with the state-of-art genetic and genomic (single cell level) strategies to expand our knowledge of the cell-cell communication, fate dynamics, and niche homeostatic of the non-neuronal cells (astrocytes and pericytes) in health, and emergency rescue when they are under stress or in disease. Ultimately, our collective efforts, alongside those of others in the field, will pave the way for groundbreaking interventions in the realm of neurological disease.