The Lyden lab has been funded by NIH, VA and AHA for over 30 years. The lab is focused on translational pre-clinical stroke modeling, pharmacology, and vascular biology. The lab has considerable experience with a variety of animal models; behavioral testing; histology; and cell biology. The lab was selected by NINDS to develop and manage the Stroke Preclinical Assessment Network (SPAN) as the Coordinating Center. Current projects include studies to determine the mechanisms of differential vulnerability in the neurovascular unit; effects of microglial activation on neuronal survival; and blood brain barrier disruption during stroke and mild traumatic brain injury.
The Lyden lab has been funded by NIH, VA and AHA for over 30 years. The lab is focused on translational pre-clinical stroke modeling, pharmacology, and vascular biology. The lab has considerable experience with a variety of animal models; behavioral testing; histology; and cell biology. The lab was selected by NINDS to develop and manage the Stroke Preclinical Assessment Network (SPAN) as the Coordinating Center. Current projects include studies to determine the mechanisms of differential vulnerability in the neurovascular unit; effects of microglial activation on neuronal survival; and blood brain barrier disruption during stroke and mild traumatic brain injury.
