Lawrence, Katherine
Assistant Professor of Research Neurology
Our research is focused on improving understanding of the brain in neurodevelopmental conditions and in typical development by using unprecedented large-scale neuroimaging datasets and advanced computational methods. Specifically, we study brain connectivity, brain function, and brain structure by analyzing diffusion-weighted MRI, resting-state and task-based fMRI, and structural MRI. We are particularly interested in understanding individual differences within and across autism and ADHD, including sex differences, age effects, and co-occurring conditions. Much of our work is conducted with the worldwide ENIGMA Consortium, for which Dr. Lawrence co-chairs the ENIGMA Autism Working Group. The long-term goal of our research is to inform how we can best support the unique strengths and needs of every neurodivergent individual.
Quadrato, Giorgia
Associate Professor of Stem Cell Biology and Regenerative Medicine
The Quadrato lab focuses on understanding the cellular and molecular basis of human brain development and mental disorders. We seek to produce meaningful work that advances the fundamental knowledge of our field and provides new tools to do it. By combining emerging models of the human brain with single-cell -omics approaches, we aim to identify brain region and cell type-specific disease mechanisms and, above all, new treatments for neuropsychiatric disorders. To improve the physiological relevance of human pluripotent stem cell-derived organoids, our lab is leveraging interdisciplinary strategies and technologies aimed at tighter regulatory control of organoid development through bioengineering approaches, along with newer unbiased organoid analysis readouts.
