Dr. Rissman is Professor Physiology and Neuroscience and founding Director of the Neuroscience Translational Research Division (NTRD) of USC’s Alzheimer’s Therapeutic Research Institute in San Diego. Dr. Rissman’s basic science research goal is to identify and validate plasma biomarkers for Alzheimer’s Disease and Related Disorders (ADRD) to better understand mechanisms of neurodegeneration and to streamline clinical trials recruitment. Work from Dr. Rissman’s lab has led to the validation of plasma biomarkers that predict AD brain neuropathology and progression of dementia. Also, through analysis of plasma-derived extracellular vesicles, his group was the first to demonstrate that TDP-43 protein within astrocyte extracellular vesicles can identify Limbic-predominant age-related TDP-43 encephalopathy (LATE).
Dr. Rissman is Professor Physiology and Neuroscience and founding Director of the Neuroscience Translational Research Division (NTRD) of USC’s Alzheimer’s Therapeutic Research Institute in San Diego. Dr. Rissman’s basic science research goal is to identify and validate plasma biomarkers for Alzheimer’s Disease and Related Disorders (ADRD) to better understand mechanisms of neurodegeneration and to streamline clinical trials recruitment. Work from Dr. Rissman’s lab has led to the validation of plasma biomarkers that predict AD brain neuropathology and progression of dementia. Also, through analysis of plasma-derived extracellular vesicles, his group was the first to demonstrate that TDP-43 protein within astrocyte extracellular vesicles can identify Limbic-predominant age-related TDP-43 encephalopathy (LATE).
