Cognitive

Lee, Darrin Jason

Associate Professor of Neurological Surgery and Psychiatry and the Behavioral Sciences (Clinical Scholar)

The focus of my laboratory is to explore the underlying mechanisms and potential of neuromodulation for cognitive dysfunction and psychiatric disorders, such as Alzheimer’s disease, Parkinson’s disease, epilepsy, depression, obsessive compulsive disorder and schizophrenia. Specifically, we utilize multiple depth electrode local field potential recordings and functional ultrasound imaging to evaluate simultaneous electrophysiology, cerebral blood flow and functional connectivity in these disorders. Using these tools, our goal is to better understand the underlying pathophysiology and optimize our neuromodulation strategies. Our aim is to translate our preclinical findings into clinically relevant neuromodulation treatments. My clinical research is focused on evaluating potential new indications and targets for neuromodulation, such as deep brain stimulation (DBS), spinal cord stimulation and focused ultrasound.

Liew, Sook-Lei

Associate Professor of Biokinesiology and Physical Therapy

The overall mission of the laboratory is to enhance neural plasticity in a wide population of individuals in order to improve their quality of life and engagement in meaningful activities. We particularly focus on individuals with stroke using big data neuroimaging approaches, along with noninvasive brain stimulation and brain computer interfaces.

Mintz, Toby

Professor of Psychology and Linguistics

My general research interests are in the cognitive mechanisms that underlie language acquisition. Ongoing and completed projects investigate the mechanisms by which infants detect words in fluent speech, how infants and very young children acquire fundamental syntactic knowledge about the language they are learning, and how toddlers learn the meanings of novel words. These research programs are connected by a common question about the nature of the mechanisms that give rise to linguistic abilities, and the effects of environmental input on these mechanisms.

Monterosso, John

Associate Professor of Psychology

Our lab is primarily focused on decision-making, especially in the context of addiction and obesity. We use self-report, behavior, and fMRI. Our lab is currently (through 2028) participating in USC’s Tobacco Center of Regulatory Science (supported by NIH & FDA).

Nastase, Samuel

Assistant Professor of Psychology

The core questions driving my research are “What is shared between individual brains?” and “How do we share our thoughts with one another?”—using language and other coordinated actions. My research combines naturalistic neuroimaging paradigms (fMRI, ECoG) and deep neural networks to better answer these questions in real-world contexts. In current work, we leverage large language models to better understand how humans use language to transmit complex thoughts from one brain to another.

Petzinger, Giselle

Associate Professor of Neurology (Clinical Scholar)

Dr. Giselle M. Petzinger is a Movement Disorders Specialist and neuroscientist in the department of neurology at USC Keck School of Medicine. Her training includes MD at USC, Neurology Residency at Yale, Fellowship at Columbia University and experimental therapeutics at the Parkinson’s Institute in the bay area. Her research involves animal models and clinical studies to investigate lifestyle on cognitive/motor function and synaptic plasticity in frontal-striatal and cerebellum circuits. Other studies include investigating the relationship between motor performance and cognitive function and related circuitry in PD and the role of compensation using behavioral, neuroimaging and neurophysiologic metrics. Her work also focuses on understanding neuro-energetic mechanisms of synaptic plasticity in PD focused on mitochondrial function and L-Lactate.