Valadez, Emilio
Assistant Professor of Psychology
Our lab focuses on understanding how early risk factors, such as temperament and early adversity, confer risk for future emotional problems among children and adolescents. More specifically, we are interested in how executive functions (assessed with a combination of behavioral, EEG, and MRI measures) moderate the psychiatric impact of early-life risk factors. Three interrelated questions spanning basic and translational work guide our research: 1) How are executive functions supported by the brain? 2) How do early risk factors alter the development of executive functions? 3) How do executive functions interact with early risk to modulate psychiatric outcomes? Ultimately, our work aims to better understand basic cognitive and developmental processes to identify novel target mechanisms for intervention.
Wang, Lu
Assistant Professor of Dentistry
Our lab aims to push the boundary of our understanding of human brain in development and related disorders with discoveries focused on non-neuronal cells, environmental stress, and genetic mutations, leveraging the stem cell-based organoid/PCCO-assembled model in combination with the state-of-art genetic and genomic (single cell level) strategies to expand our knowledge of the cell-cell communication, fate dynamics, and niche homeostatic of the non-neuronal cells (astrocytes and pericytes) in health, and emergency rescue when they are under stress or in disease. Ultimately, our collective efforts, alongside those of others in the field, will pave the way for groundbreaking interventions in the realm of neurological disease.
