USC study maps brain network changes linked to bipolar disorder severity and treatment

The largest diffusion MRI network analysis of bipolar disorder to date reveals subtle but widespread differences in brain communication pathways involved in emotion, reward, and cognitive control. The study’s authors include NGP Student Melody J.Y. Kang and NGP Faculty Neda Jahanshad and Christopher R.K. Ching.

This brain graph maps connections between brain regions, formed by white matter pathways that carry signals across the brain. It highlights the connections that differ in bipolar disorder, particularly in networks involved in emotion regulation, reward processing, attention, and self-reflection. Photo/Stevens INI

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