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Mark S. Humayun

Cornelius J. Pings Chair in Biomedical Sciences
University Professor of Ophthalmology, Biomedical Engineering, Cell & Neurobiology
Co-Director, USC Eye Institute
Director, USC Sensory Science Institute

Mark S. Humayun

Research Topics

  • Electrical stimulation of the retina
  • Retinal prosthesis
  • Retinal disease
  • Instrumentation for vitreoretinal surgery

Research Images

Artificial Retina Epiretinal Prosthesis

Contact Information

Mailing Address Doheny Eye Institute
1355 San Pablo Street, DVRC 119
Los Angeles, CA 90033
Office Location
Office Phone (323) 442-6523
Lab Location
Lab Phone
Fax (323) 442-6755
Office Location



  • Duke University Medical School, M.D.
  • University of North Carolina, Biomedical Engineering, PhD.

Selected Publications

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  • Ameri H, Ratanapakorn T, Rao NA, Chader GJ, Humayun MS. (2008)  Natural course of experimental retinal vein occlusion in rabbit; arterial occlusion following venous photothrombosis. Graefes Arch Clin Exp Ophthalmol. (In press). PubMed
  • Lo R, Li PY, Saati S, Agrawal R, Humayun MS, Meng E. (2008) A refillable microfabricated drug delivery device for treatment of ocular diseases. Lab Chip. 2008 Jul;8(7):1027-1030. PubMed
  • de Balthasar C, Patel S, Roy A, Freda R, Greenwald S, Horsager A, Mahadevappa M, Yanai D, McMahon MJ, Humayun MS, Greenberg RJ, Weiland JD, Fine I. (2008)  Factors affecting perceptual thresholds in epiretinal prostheses. Invest Ophthalmol Vis Sci. 49(6):2303-2314. PubMed
  • Lim TH, Humayun MS, Yoon YH, Kwon YH, Kim JG. (2008) The efficacy of retrobulbar block anesthesia only in pars plana vitrectomy and transconjunctival sutureless vitrectomy. Ophthalmic Surg Lasers Imaging. 39(3):191-195. PubMed
  • Ahuja AK, Behrend MR, Whalen JJ, Humayun MS, Weiland JD. (2008) The dependence of spectral impedance on disc microelectrode radius. IEEE Trans Biomed Eng. 55(4):1457-1460. PubMed
  • Ameri H, Kim JG, Ratanapakorn T, Chader GJ, Humayun MS. (2008) Intravitreal and subretinal injection of tissue plasminogen activator (tPA) in the treatment of experimentally created retinal vein occlusion in rabbits. Retina. 28(2):350-355. PubMed
  • Fang SY, Deboer CM, Humayun MS. (2008) Performance analysis of new-generation vitreous cutters. Graefes Arch Clin Exp Ophthalmol. 246(1):61-67. PubMed
  • Ameri H, Chader GJ, Kim JG, Sadda SR, Rao NA, Humayun MS. (2007) The effects of intravitreous bevacizumab on retinal neovascular membrane and normal capillaries in rabbits. Invest Ophthalmol Vis Sci. 48(12):5708-5715. PubMed
  • Huang CC, Zhou Q, Ameri H, Wu da W, Sun L, Wang SH, Humayun MS, Shung KK. (2007) Determining the acoustic properties of the lens using a high-frequency ultrasonic needle transducer. Ultrasound Med Biol. 33(12):1971-1977. PubMed
  • Huang CC, Ameri H, Deboer C, Rowley AP, Xu X, Sun L, Wang SH, Humayun MS, Shung KK. (2007)  Evaluation of lens hardness in cataract surgery using high-frequency ultrasonic parameters in vitro. Ultrasound Med Biol. 33(10):1609-1616. PubMed